Barrier

At SID 2019 | Wednesday, May 8, 2019 | 11:00 am-2:00 pm CST

Hilton Chicago, Continental C | Chicago, IL, USA

Join the IEC at a special symposium to discuss the barrier in atopic dermatitis. This symposium will take place prior to the Society for Investigative Dermatology (SID) Meeting in Chicago, IL, USA.  Funding for this symposium was provided, in part, by an unrestricted educational grant from Dermavant Sciences, Inc. In addition to this symposium, the IEC is providing the Roadmap for Atopic Dermatitis at SID 2019. This downloadable PDF helps you make the most of SID 2019 by highlighting the symposia, posters, and e-poster sessions that focus on atopic dermatitis!

PROGRAM CHAIRS

• Amy Paller, Chicago, IL, USA
• Lisa Beck, Rochester, NY, USA
• Masa Amagai, Tokyo, Japan
• Kenji Kabashima, Kyoto, Japan

• Discuss new data about barrier abnormalities in AD.
• Show how emerging therapeutic interventions can improve the barrier.

AGENDA

11:00–11:05 am Welcome Emma Guttman, New York, NY

11:05–11:10 am Program Overview Amy Paller, Chicago, IL, USA

11:10–11:30 am Basic Structure of the Epidermis Akiharo Kubo, Tokyo, Japan

11:30–11:45 am Role of Ephrins in Tight Junction Function Bethany Perez White, Chicago, IL, USA 11:45 am–12:05 pm

Abstract Presentations – Part 1 Moderator: Lisa Beck, Rochester, NY, USA Abstract #324  - A potential role of galectin-7 as a stabilizer for IL-4/IL-13-induced barrier disruption in atopic dermatitis. T. Shimauchi, T. Umayahara, M. Iwasaki, M. Aoshima, S. Nakazawa, Y. Tokura, Department of DermatologyHamamatsu University School of Medicine, Hamamatsu, Japan. Abstract #565 - Improvement in skin inflammation and barrier function biomarkers with crisaborole treatment in atopic dermatitis (AD). E. Guttman-Yassky, A.B. Pavel, A. Diaz, Y. Estrada, Icahn School of Medicine at Mount Sinai, New York, New York, United States | J.L. Werth, C. Zang, M.A. Zielinski, B. Vlahos, Pfizer Inc., Collegeville, Pennsylvania, United States | I. Vranic, Pfizer Inc., Walton Oaks, Surrey, United Kingdom |V.S. Purohit, W.C. Ports, Pfizer Inc., Groton, Connecticut, United States | E. Saint-Cyr-Proulx, R. Bissonnette, Innovaderm Research, Montreal, Quebec, Canada

12:05–12:25 pm Lunch Available for Participants

12:25–12:45 pm Stratum Corneum Proteins Matthias Schmuth, Innsbruck, Austria

12:45–1:05 pm Epidermal Proteases Alain Hovnanian, Paris, France

1:05–1:15 pm Abstract Presentations – Part 2 Moderator: Masa Amagai, Tokyo, Japan Abstract #993 - Molecular abnormalities of early-onset pediatric atopic dermatitis are captured by tape strips. A. Diaz, A.B. Pavel, R. Li, M. Fernandes, X. Peng, Y. Estrada, E. Guttman-Yassky, Dermatology, Icahn School of Medicine at Mount Sinai, New York, New York, United States | A.S. Paller, Dermatology, Northwestern University, Chicago, Illinois, United States | J.G. Krueger, Dermatology, The Rockefeller University, New York, New York, United States

1:15–1:35 pm Epidermal lipids in health and disease Jeroen van Smeden, Leiden, The Netherlands

1:35–1:50 pm Measurement of Barrier Components and Function Eric Simpson, Portland, OR, USA

1:50–2:00 pm Closing Comments­ Kenji Kabashima, Kyoto, Japan